Scrub typhus, also known as scrub typhus, is an important zoonotic disease prevalent in Asia and the Pacific. The pathogen causing the disease is *Orientia tsutsugamuchi*, an obligate intracellular parasite, Gram-negative, with several antigen-specific serotypes, including Gilliam, Karp, Kato, and Kawasaki. In my country, scrub typhus is widespread, with wild rodents serving as natural reservoir hosts. Humans are primarily infected through bites from the chigger mite during outdoor activities. Due to the lack of characteristic clinical symptoms (primarily fever, with some patients exhibiting eschar), patients are often misdiagnosed or missed, leading to serious consequences. Our company has developed a human IgM antibody diagnostic kit targeting the 56 kDa antigen of the pathogen, for both early diagnosis of human infection and confirmation of past infections. The total antibody diagnostic kit can also be used for seroepidemiological surveys in humans and animals. Validated on a large number of clinical specimens, this kit demonstrates good specificity and sensitivity, effectively identifying serotypes such as Gilliam, Karp, Kato, and Kawasaki.

An indirect ELISA detection system was constructed using a 56 kDa protein as the coating antigen and HRP-labeled mouse anti-human IgG monoclonal antibody as the secondary antibody. This system confirms infection by detecting Orientia scrub typhus-specific IgG antibodies in the serum of convalescent patients.

Product Code: Scrub Typhus Patient IgG Diagnostic Kit (ES41003)